The NFL released its full 272-game schedule Wednesday. Here's a look at the most interesting matchup in each of the 18 weeks.

Here's an entire listing of the Monday night schedule. Each game can be seen on ESPN (unless noted otherwise), with select matchups also being shown on the "ManningCast," which is aired on ESPN2 and on ESPN+. We've also included a ranking of the entire "Monday Night Football" schedule.

While the official dates and times for the 2025 NFL season won’t be released until later this spring, we do know who your favorite team will be playing and where.

The Los Angeles Rams will be a hot matchup in 2025. The defending NFC West champions have an interesting schedule that features a lot of quality teams and some familiar faces. That alone makes the lineup compelling,

The 49ers endured a disappointing 2024 NFL season, but it has set them up for potential success in 2025. San Francisco is playing a fourth-place schedule after finishing last in the NFC West. That set them up with matchups against the Bears, Browns and Giants.

The season openers between the Dallas Cowboys and Philadelphia Eagles and Baltimore Ravens-Buffalo Bills and Detroit Lions-Green Bay Packers are among the most intriguing matchups to launch the 2025 NFL campaign.

Spotify | YouTube Matt Harmon and Andy Behrens react to the NFL schedule release and identify the ten most important fantasy matchups of the season. The two also debate if the NFL schedule makers got it right with certain teams and their amount of primetime games and which Week 17 matchups could

The Atlanta Falcons are likely to have several key December games during the 2025 NFL regular season. The 2025 NFL schedule is finally here. Atlanta Falcons fans will be happy to hear that their team will play five primetime games and a Sunday morning contest from Europe.

Will the 49ers roll into the playoffs? Can the Giants, Lions and Cowboys overcome tough slates? Let's size up schedule reveal fallout.

The NFL announced six of seven matchups for their 2025 international series on Tuesday, including back-to-back road games for the Minnesota Vikings.

The NFL announced team-by-team opponents and select prime-time games for the 2025 preseason on Wednesday.