and ribosomal RNAs (rRNAs) and degradation of many non-coding RNAs including those that arise from bidirectional transcription or transcription from enhancers. The eukaryotic nuclear RNA exosome ...

His interest in large macromolecular assemblies led him for his postdoctoral work to the Department of Molecular Biophysics and Biochemistry at Yale University where he determined the atomic structure ...

First, three initiation factor proteins (known as IF1, IF2, and IF3) bind to the small subunit of the ribosome ... a sample of 170 prokaryotic and 120 eukaryotic proteins (Flinta et al., ...

The expression of many eukaryotic genes is regulated at the level of translation initiation. The first step in the initiation process is binding of the small ribosomal subunit (40S) to the mRNA.