Amid Israel's massive airstrikes on Iran and the Islamic nation's missile response in two barrages Friday aimed at the Jewish state, residents in both nations are on high alert.

Iran is undergoing a forceful counterattack after Israel's strikes, while experts analyze whether Iran will target American forces in the region or at home.

The US military has helped shoot down Iranian missiles that were headed toward Israel, two American officials said on Friday, according to Reuters News Agency. We have more on Netanyahu's statement now.

Follow the latest news after Israel launched strikes at Iran, a dramatic escalation in long-running tensions between the two countries.

Russian President Vladimir Putin held phone calls with Israeli Prime Minister Benjamin Netanyahu and Iranian President Masoud Pezeshkian on Friday after Israel hit Iran in a series of strikes.

U.S. stock futures tumbled after Israel launched airstrikes against Iran. Israel’s defense minister Israel Katz declared a special state of emergency following the attack. Iran has launched retaliatory drone strikes on Israel.

Sen. Chris Murphy (D., Conn.), who sits on the Senate Foreign Relations Committee, said Israel’s attack on Iran was intended to thwart the Trump administration’s negotiations with Iran, and risks a regional war.

Israel launched 200 warplanes on some of Iran's core nuclear and missile programs in what's been dubbed the "Rising Lion" operation. Tehran quickly retaliated by sending 100 drones into Israel, which the Israel Defense Forces said were mostly intercepted.