Skenes fell to 0-4 in five career starts against the Cardinals after a 2-1 loss Tuesday night. It's the most starts by a Pirates pitcher to begin a career against St. Louis without a win since JT Brubaker went 0-6 in eight starts in 2021 and 2022.

The St. Louis Cardinals won a closely fought encounter against the Pittsburgh Pirates in a closely contested 2-1 win, and in the process, extended their unbeaten run over Paul Skenes, who is still winless against them.

Two RBIs from Alec Burleson, seven innings from starter Matthew Liberatore and a save in his first opportunity by Gordon Graceffo helped the Cardinals beat the Pirates 2-1 on Tuesday.