EurekAlert!

Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...
Nature

Anticancer compounds that exploit a compromised checkpoint in the cell cycle

Many cancer-driving mutations disable a key checkpoint in the cell’s cycle between growth and division, resulting in unchecked activity of the E2F family of transcription factor proteins. A set of ...
Medical Xpress

Cell Physiological Phenomena: News and Research on M Phase Cell Cycle Checkpoints

In a new paper published in Cancer Research, researchers at MUSC Hollings Cancer Center have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can ...
Medical Xpress

M Phase Cell Cycle Checkpoints

In a new paper published in Cancer Research, researchers at MUSC Hollings Cancer Center have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can ...