An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

DNA-PK can help repair DNA double-stranded breaks in one of two ways. For breaks with missing information, it can target enzymes that can fill in missing nucleotides — sort of like a needle and thread ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

Ultraviolet (UV) rays from sunlight can cause DNA damage that leads to skin aging and cancer. Fortunately, our bodies have a highly efficient repair system capable of swiftly identifying and repairing ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the effects aren't just skin deep. Inside the body, DNA is literally being torn ...

(Nanowerk News) A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA. Such mistakes are frequent in code-copying process in ...

A team of researchers has made a discovery that may have implications for therapeutic gene editing strategies, cancer diagnostics and therapies and other advancements in biotechnology. A team of ...

(Nanowerk News) A team of researchers from Michigan State University’s College of Veterinary Medicine has made a discovery that may have implications for therapeutic gene editing strategies, cancer ...