Scientists have found that the activity of proprotein covertases, the enzymes that turn-on proteins, is regulated by the location of the enzyme inside the cell. The study uses a novel biosensor, CLIP, ...

An enzyme found in the brain acts as a major regulator of body weight, Yale researchers have discovered. In a new study, they found that removing the enzyme from neurons in a part of the brain known ...

Researchers present novel therapeutics that rejuvenate a previously undruggable mitochondrial regulator of aging through a new mode of enzyme activation. Leveraging a newly identified biophysical ...

Even well-studied proteins can reveal surprises. University of Iowa scientists have discovered a new enzyme activity for the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is the ...

A large team of researchers led by Wouter Karthaus, head of the Endocrine Therapy Resistance and Molecular Genetics Lab at ...

The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis. Researchers led by Martin ...

Enzymes are crucial for speeding up slow chemical reactions. Anyone who has worked in a genetics lab is familiar with a common enzyme called Taq polymerase, because it's a reliable workhorse that can ...

Switching off a “master regulator” of the epigenome called TET2 may protect the brain from the inflammatory damage and neurodegeneration caused by Parkinson disease, according to recent study findings ...