It's commonly accepted that protein folding/misfolding are alternative reactions of unfolded proteins but the principles governing this remain unknown. Here, researchers describe a general concept ...

Max Planck scientists find a novel way to construct transition states for protein folding reactions. Scientists continue to be puzzled by how proteins fold intotheir three-dimensional structures.

The rate of folding of αLP R102H/G134S catalyzed by Pro-3 was determined with the trypsin-based folding kinetics assay developed for the characterization of wild type αLP. At a concentration of 75 μM ...

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Researchers from Osaka University have described the link between accurate protein folding and misfolding that can lead to the formation of amyloid fibers, which are implicated in neurodegenerative ...