Sometimes, in genetics, two wrongs do make a right. A research team has recently shown that two harmful genetic variants, ...

We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research team has proposed a cutting-edge research strategy that leverages artificial ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...

An HIV-derived nucleoside therapy now treats rare genetic diseases by restoring mitochondrial DNA and improving muscle ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research ...

Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Randomized trials of platelet function and genetic testing to guide antiplatelet decisions following PCI have produced notoriously mixed results: now, an updated consensus document aims to fill some ...

Humanized mouse models are vital for studying human gene function, but fully replacing mouse genes with complete human ...