Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation. Most multi subunit ion channels exist in two functional states, ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 24 (June 16, 2020), pp. 13437-13446 (10 pages) Pentameric ligand-gated ion channels (pLGICs) are ...
BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.
Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies.
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