Figure 2: KSRP regulates pre-let-7a-1 processing and controls the expression of certain miRNAs. Figure 3: KSRP is a component of the microprocessor complex, interacts with pri-let-7a-1 favouring its ...
Let-7 is an important tumor-suppressive microRNA (miRNA) that acts as an on-off switch for cellular differentiation and regulates the expression of a set of human oncogenes. Binding of the human KSRP ...