Microscopy images of antigen-inexperienced (‘naïve’) mouse CD8 T cells (green). A subset of these cells expresses Dapl1 protein (red), identifying a population committed to a memory stem-like lineage.

A team of immunologists at the University of Massachusetts Amherst has turned what we know about T-cells, one of the most important parts of the body's immune system, on its head, opening the door to ...

Researchers have discovered a three-drug combination that enhances the generation of CAR-T cells, a type of cancer immunotherapy, and could improve CAR-T cell production for clinical treatments. The ...

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...

Although CAR T-cell treatment can lead to clinical remissions in patients with hematological malignancies, relapse rates ultimately remain high. Previous research has found that T memory stem cell ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

Sangamo BioSciences, Inc. (Nasdaq: SGMO), the leader in therapeutic genome editing, announced the presentation of Phase 2 data from two of the Company's ongoing clinical trials (SB-728-1101 Cohort 3* ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...