Methotrexate is a primary disease-modifying anti-rheumatic drug (DMARD) used to treat rheumatoid arthritis (RA) by reducing inflammation and suppressing the immune system. The American College of ...

Methotrexate, a common treatment for rheumatoid arthritis, can cause folate deficiency. Natural folate can be consumed from leafy vegetables. A doctor may prescribe folic acid supplementation to help ...

Methotrexate is a prescription medication. It comes in four forms: self-injectable solution, injectable IV solution, oral tablet, and oral solution. For the self-injectable solution, you can receive ...

Early aggressive treatment of rheumatoid arthritis is associated with improved disease control, slower radiological progression and improved functional outcomes. Tumor necrosis factor blocking therapy ...

A post-hoc analysis of two phase III, randomized, controlled studies has suggested that folic acid decreases the efficacy of methotrexate in patients with rheumatoid arthritis (RA). Folic acid is used ...