Somatic loss-of-heterozygosity can result in the complete loss of function of tumor suppressor genes in human cancer. Mitotic recombination between homologous chromosomes can cause loss of ...

This is a preview. Log in through your library . Abstract The biosynthesis of thymine nucleotides in Saccharomyces cerevisiae can be inhibited either by genetic lesions in the structural gene for ...

A team of researchers led by Leonid Kruglyak have developed a technique using the gene editing system CRISPR to rapidly identify gene variants. The findings could significantly improve efforts to map ...

Chromosomes undergo precise structural changes at a molecular level during the different phases of cell division. These changes occur at a high level of accuracy to prevent genome instability. Genome ...