T lymphocytes, unlike other hematopoietic cells, differentiate in the thymus, a specialized organ that provides a unique environment for the acquisition of immunological competence. Analysis of the ...
In thymic epithelial cells, the research team upregulated a transcription factor called Forkhead box N1 (FOXN1), which had previously been implicated in age-related thymus shrinkage. Consequently, the ...
Researchers from the Organoid group have developed a new organoid model that can be used to study the thymus. The organoids, derived from mouse thymus tissue, specifically model thymic epithelial ...
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