Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including ...
2don MSN
Higher maternal blood pressure increases the risk of pregnancy complications, study concludes
Helping women to keep their blood pressure at normal levels could reduce their risk of experiencing pregnancy complications, ...
Traditional epidemiological studies have identified numerous potential risk factors, but observational studies have struggled to establish causal links due to confounding factors and reverse causation ...
New genetic evidence links higher BMI and IBD to hidradenitis suppurativa risk, while smoking remains unclear. Read more.
The schematic illustrates the comprehensive pipeline for Mendelian randomization analysis, starting with multi-omics data inputs from GWAS, eQTL, and pQTL studies, sourced from major databases such as ...
It has been argued that survival bias may distort results in Mendelian randomization studies in older populations. Through simulations of a simple causal structure we investigate the degree to which ...
Increased BMI and IBD have causal effects on the risk of hidradenitis suppurativa, as shown by Mendelian randomization analysis. Moderate genetic correlations were found between HS and BMI, smoking, ...
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