A previous study demonstrated that power against the (unobserved) true effect for the primary end point (PEP) of most phase III oncology trials is low, suggesting an increased risk of false-negative ...

Cox model marginal survivor function and pairwise correlation models are specified for a multivariate failure time vector. The corresponding mean and covariance structure for the cumulative baseline ...

In nonparametric multivariate regression analysis, we seek methods to reduce the dimensionality of the regression function to bypass the difficulty caused by the curse of dimensionality. The original ...