PINNACLE sheds light on how these cells and tissues influence the same proteins differently, something not possible with current models. Depending on the specific cell type in which a protein network ...

Scientists have identified five hub genes that might be associated with severe coronavirus disease 2019 (COVID-19) outcomes in patients with diabetic kidney disease. The study is currently available ...

In amyotrophic lateral sclerosis and frontotemporal dementia, loss of nuclear TDP-43 mucks up splicing of many transcripts, squelching expression of the associated proteins. However, this missplicing ...

A review published in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research ...

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways ...