LONDON, England—Patients with pulmonary hypertension (PH) undergoing TAVR for severe symptomatic aortic stenosis fare significantly worse than those without increased pre-interventional pulmonary ...

Candesartan (CHARM-P) 3023 EF >40%; mean age: 67; NYHA class II–IV; prior hospitalization Primary: cardiovascular death; HF-related hospitalization Secondary: composites of primary outcome ...

There are two parts to the pumping action of the heart. The first part is called diastole, when blood collects in the lower heart chambers (right and left ventricles) as it is pushed through the ...

Repolarization dispersion has been linked to echocardiographic measures of diastolic dysfunction in past research, and a recent study found it potentially indicative of pulmonary arterial hypertension ...

Because life expectancy and the prevalence of risk factors such as hypertension, obesity and diabetes are rising globally, heart failure (HF) is growing into a major health problem. Impairment of left ...

Chronic heart failure occurs when either the left ventricle, the right ventricle, or both require elevated filling pressures to maintain cardiac output. Heart failure is a syndrome, not a specific ...

Diastolic dysfunction is a heart condition that affects the organ’s capacity to fill with an adequate amount of blood during diastole. Diastole is the phase of the cardiac cycle when the heart relaxes ...

Diastolic dysfunction occurs when the left ventricular myocardium is non-compliant and not able to accept blood return in a normal fashion from the left atrium. This can be a normal physiologic change ...