The mammalian target of rapamycin (mTOR) protein complexes regulate cell growth in response to nutrients. However, the first step of this pathway (how nutrients regulate activation of mTOR complexes) ...

Amino acids act as nutrient signals to induce cell growth in addition to their role as protein building blocks. Cells can sense the availability of extracellular and intracellular amino acids and ...

Amino acids are essential for cell growth and metabolism. Amino acid and growth factor signaling pathways coordinately regulate the mechanistic target of rapamycin complex 1 (mTORC1) kinase in cell ...