T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

Immunotherapy has emerged in recent years as a new cancer treatment that is gentler than traditional chemotherapy and causes ...

Researchers at the Max Delbrück Center have found that a cellular housekeeping mechanism called autophagy plays a major role ...

Universal CAR T cells produce rapid remissions and enable allogeneic stem cell transplants in patients with relapsed or refractory T-cell acute lymphoblastic leukemia.

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Researchers released a consensus statement with recommendations to update T cell nomenclature and improve communication ...

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets ...