Nature

Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus

Figure 1: Mst1 deficiency causes impaired migration of SP thymocytes within thymic tissues. Figure 2: Requirement of LFA-1and ICAM-1 for efficient migration in thymic tissues. Figure 3: ...

First Patient Dosed in SAB BIO’s SAFEGUARD Clinical Trial of SAB-142 for the Treatment of Stage 3 T1D

Enrollment in the SAFEGUARD trial is ongoing at multiple centers globallyCompany on-track to share Phase 2b data in 2H 2027MIAMI, Dec. 18, 2025 ...

SAB Biotherapeutics, Inc.: SAB BIO Announces Positive Confirmatory Clinical Results from the Phase 1 Study of SAB-142 in Development for the Treatment of Stage 3 T1D

Phase 1 data confirms SAB-142 does not cause serum sickness and has low/no immunogenicity at any dose and in all cohorts, including redosed healthy volunteersStudy results support the chronic dosing ...
BioWorld

Sab's fully human anti-thymocyte immunoglobulin cleared to enter clinic in Australia for type 1 diabetes

Sab's fully human anti-thymocyte immunoglobulin cleared to enter clinic in Australia for type 1 diabetes Oct. 20, 2023 ...