Thymocyte development in ZORI mice is restored by expression of a transgene encoding a preassembled TCRαβ. Zfp608 expression is maintained in ZORI mice; however, in normal mice, Zfp608 expression ...
The development of new experimental tools is helping to unravel the molecular secrets of cell differentiation. The identification, by gene chip technology, of a HMG box protein called TOX has yielded ...
Activation of the small G protein Ras is required for thymocyte differentiation. In thymocytes, Ras is activated by the Ras guanine exchange factors (RasGEFs) Sos1, Sos2, and RasGRP1. We report the ...
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