The latticework of extracellular protein that surrounds brain cells forms a particularly dense mesh around fast-spiking interneurons. Why do these cells need such thick coats? In the July 17 Nature ...

Electron microscope image of neurons in the cerebellum. This slice through the cells in the cerebellum shows a dendritic branch of a Purkinje cell and its side arms (yellow) receiving several ...

A researcher has developed a new model that provides a holistic view on how our brain manages to learn quickly and forms stable, long-lasting memories. Their study sheds light on the crucial role of ...

To stay in balance, the brain depends on two types of neurons: Excitatory neurons (in white), which increase activity, and inhibitory neurons (in black), which damp down signals. Scientists have now ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Unlocking the intricate secrets of the human brain's inner workings has long been a pursuit of scientific inquiry. In a groundbreaking study by Shapson-Coe et al., researchers utilized cutting-edge ...

What goes wrong first in the Alzheimer’s disease brain? Scientists led by Marc Aurel Busche of the U.K. Dementia Research Institute at University College London may have an answer. In the May 7 Neuron ...

A study of cells from 84 cadaver brains suggests that Alzheimer's has two distinct phases, and that one type of neuron is especially vulnerable. "There's an early phase where there's a very slow ...