LOUISVILLE, Ky. — Several agencies are responding to a plane crash involving a UPS cargo plane near Louisville's Muhammad Ali ...

Jesse Robinson was shot and killed by Muncie police after allegedly shooting dozens of rounds from his porch into surrounding ...

INDIANAPOLIS — Indiana's Attorney General Todd Rokita wants President Donald Trump to send the National Guard to Indianapolis ...

COPD is a group of lung diseases that get worse over time. It prevents airflow to the lungs, causing breathing problems and ...

Republican Lt. Gov. Winsome Earle-Sears and Democratic U.S. Rep. Abigail Spanberger seek to replace term-limited Republican ...

California voters have just one yes-or-no question on the ballot, but it could have a big impact on next year's midterm ...

Jalea Brooks previews the events happening around Indy in November including ...

The Indianapolis Colts have traded two first-round draft picks in 2026 and 2027 and wide receiver AD Mitchell to the New York Jets for cornerback Sauce Gardner.

George W. Bush’s vice president died Monday from complications of pneumonia and cardiac and vascular disease, his family said Tuesday in a statement.

Democrat Mikie Sherrill and Republican Jack Ciattarelli are the nominees to succeed term-limited Democratic Gov. Phil Murphy ...

SiriusXM is ringing in the holidays with 23 ad-free music channels, including returning favorites like Hallmark Radio and ...

Disasters at Chernobyl, Three Mile Island and Fukushima Daiichi have made many people scared of nuclear power. The company ...