From the Human Genome Project to large-scale initiatives like the UK Biobank and The Cancer Genome Atlas (TCGA), the recent ...

Watching mainstream science in America under attack by the US federal and many state governments, most scientists and health ...

The epithelial–mesenchymal transition (EMT) is a source of cancer cell plasticity and tumour heterogeneity, and is ...

For decades, the biology of the intestinal stem cells was considered analogous to that of well-studied hematopoietic stem ...

Mitogen‐activated protein kinase (MAPK) cascades are important signaling modules regulating diverse biological processes. During the past 20 years, much progress has been made on the functions of MAPK ...

image image The study demonstrates that fibroblast growth factors suppress the cellular interferon response and thereby promote viral replication. Inhibition of FGF signaling has the opposite effect, ...

Genome‐, transcriptome‐ and proteome‐wide measurements provide insights into how biological systems are regulated. However, fundamental aspects relating to which human proteins exist, where they are ...

Human microproteins encoded by long non‐coding RNAs (lncRNA) have been increasingly discovered, however, complete functional characterization of these emerging proteins is scattered. Here, we show ...

The recent scandal surrounding Facebook and Cambridge Analytica 5 shows that these aspects of security and privacy are often not taken into account. Cambridge Analytica, a British consulting firm, was ...

Gpx4 and TRF are PPARα target genes involved in ferroptosis regulation. Loss of PPARα aggravates iron overload‐induced ferroptosis in vivo, while activation of PPARα is sufficient to largely alleviate ...

Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

Plant and animal perception of microbes through pathogen surveillance proteins leads to MAP kinase signalling and the expression of defence genes. However, little is known about how plant MAP kinases ...