An ongoing open-label extension study suggests that the therapy's benefits may extend through at least 52 weeks. Deupirfenidone (LYT-100), a next-generation antifibrotic therapy, demonstrated a ...

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare acquired autoimmune neurological disorder in which both T-cell-mediated and humoral immune mechanisms target healthy myelinated ...

In diagnosed cases of cutaneous mastocytosis, investigations to rule out systemic mastocytosis may be appropriate. A young child with a small chest lump and anemia was found to have cutaneous ...

My recent liver biopsy was a case study of Murphy’s Law in action. And as I share the details of my saga, I’m mindful that my experience is the exception, not the rule. I do not want to discourage ...

In classical PNH, disease is present with the absence of bone marrow disease. 3 Patients with classical PNH typically have severe intravascular hemolysis along with an elevated reticulocyte count, a ...

Nusinersen, an SMN2-targeted antisense oligonucleotide drug administered by intrathecal injection, was able to improve motor function and survival. Treatment with nusinersen can improve motor function ...

In CIDP, SOC therapies (immunoglobulins/corticosteroids) are burdensome, have variable efficacy, and significant side-effects. Two phase 3 clinical trials, MOBILIZE ...

This unique case underscores the importance of meticulous prenatal and postnatal immunologic workup when alloimmune conditions are suspected. A 37-year-old multiparous woman with RhD alloimmunization ...

New research indicates that obinutuzumab is a potentially effective and cost-effective treatment for patients with rituximab-resistant AAV. Obinutuzumab therapy demonstrated immunological superiority ...

The study showed a significant increase in antibody-dependent cellular cytotoxicity for GASDALIE, AFUC, and AFUC GASDALIE variants (40%-49%) compared with wild-type ...

Pediatric patients with ALL experience, on average, about 15 different symptoms in their chemotherapy journey. Pediatric patients with acute lymphoblastic leukemia (ALL) experience a wide range of ...

All 5 patients who switched from eculizumab remained relapse-free while being treated with satralizumab. Satralizumab after eculizumab is effective and well tolerated in patients with neuromyelitis ...