News

With two amyloid immunotherapies on the market in many countries, scientists are eager for information on how durable their clinical effects will be. At this year’s Alzheimer’s Association ...
Statins do not help prevent Alzheimer’s disease, but another cholesterol-controlling drug just might. Obicetrapib blocks cholesteryl esters being transferred from the “good” high-density lipoproteins ...
Computational biology has put the human brain vasculature in its crosshairs. On July 23 in Neuron, scientists led by Andrew Yang, University of California, San Francisco, report a multiomic approach ...
The investigational drug obicetrapib blocks the transfer of cholesteryl esters from high- to low-density lipoprotein. In a cardiovascular disease trial, it reduced plasma p-tau217.
Scientists trained three machine-learning algorithms to find variants that distinguish AD cases from controls among more than 40,000 European AD Biobank samples. ML found as many genome-wide ...
In Alzheimer’s disease, some microglia gather around plaques, while others seem aloof, opting to keep their distance. In the July 14 Nature Neuroscience, scientists led by Marco Prinz at the ...
Artificial intelligence learns to recognize subtle biochemical features of γ-secretase substrates. Screening potential transmembrane proteins identifies 250 substrates, including 160 novel ones. These ...
Why do some people age rapidly while others maintain their health well into their 80s and 90s? A new study suggests that maintaining “youthful” organs may be key. Scientists led by Tony Wyss-Coray at ...
Machine learning software sharpens the diagnostic utility of FDG PET scans. StateViewer told apart nine neurodegenerative diseases with 93 percent accuracy. Using the program made radiologists three ...
p-Tau217 might be the Benjamin Button of biomarkers—starting off old and ending up young. Seriously, p-tau217 is unusually high at birth before waning with age, scientists report. In a cross-sectional ...
Discover a comprehensive list of brain banks worldwide, facilitating Alzheimer's and Parkinson's research on Alzforum.