San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

The Arizona Cardinals and San Francisco 49ers entered the season final both struggling, Arizona having lost five of six and ...

The Miami Dolphins are set to own the No. 13 pick in the 2025 NFL draft. After losing Sunday against the New York Jets, the ...

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted ...

The New England Patriots wasted no time responding to their 4-13 finish on Sunday, firing coach Jerod Mayo hours after the ...

For the past two weeks — since their elimination in Carolina — the Cardinals have insisted on the importance of winning games ...

The Mount Union and North Central college football teams meet in the Amos Alonzo Stagg Bowl. Get live NCAA D3 title game ...

Jennings got into fights on consecutive plays and fell 25 yards short of a career milestone. But he didn't seem to mind.

The Arizona Cardinals enter the offseason coming off a victory, as they defeated the San Francisco 49ers on Sunday. Here are ...

The 2024 season came to a fitting end for the San Francisco 49ers on Sunday, based on how things went for the team over the ...

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

Check out Kyler Murray's postgame interview after the Arizona Cardinals defeated the San Francisco 49ers in the last game of the regular season.