Cyclone is a portable gene-switch system that uses acyclovir to reversibly control gene expression with minimal toxicity.

South Rampart Pharma is working to develop an oral small molecule non-opioid pain treatment which has generated early positive clinical data as a therapy for acute and chronic pain, as well as ...

Study reshapes view of how a common leukemia begins and could point to new therapeutic strategies targeting a common weakness.

Tumors were eradicated in 30% of mice receiving cGAS LNPs injected into the tumor, in combination with immune checkpoint blockade.

The future depends on collaboration between pharma and diagnostics companies to implement strategies that accelerate innovation, ensure regulatory alignment, and deliver local access at global scale ...

A new single-cell brain atlas reveals how midbrain neurons develop, helping refine Parkinson’s disease models and improve cell therapy protocols.

The Cyclin A2 gene (CCNA2), which turns off after birth in humans, can promote cardiac repair in adult human cardiomyocytes.

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

Synthetic biology is ready for the next developmental milestone and America’s leadership depends on getting the financing right.

Existing oncology therapeutics are either so specific they can target only part of a tumor, or so generalized they kill healthy tissue.

In industrial engineering, digital twins—computer models of systems or processes—let scientists try out ideas before finalizing designs. In addition, on the factory floor, twins can model processes in ...

From designing proteins not found in nature to extending healthy lifespan, Retro Biosciences is applying AI models to advance ...