Half maximal effective concentration (EC50) is a measure of the concentration of a drug, antibody or toxicant which induces a biological response halfway between the baseline and maximum …

The EC50 is the concentration of a drug that gives half-maximal response. The IC50 is the concentration of an inhibitor where the response (or binding) is reduced by half.

Mar 6, 2025 · EC 50 is the concentration of the compounded needed to induce a 50% response (meaning it is half the maximal effective concentration). Like IC 50, lower EC 50 values mean …

Nov 20, 2025 · EC50 is a key pharmacology metric that defines a drug's potency, representing the concentration needed to achieve 50% of its maximum effect. Learn how it's calculated and its …

Mar 20, 2025 · EC50 stands for "half maximal effective concentration" and is a crucial pharmacological parameter used to quantify the relationship between the concentration of a …

EC50 stands for Effective Concentration, 50%. It represents the concentration of a substance, such as a drug or toxicant, that induces a biological response halfway between the baseline …

While inhibition is critical, sometimes the goal is the opposite: to activate a response. This is where the EC50 (Effective Concentration 50) comes into play. What it means: The EC50 is the …

This article provides minimum requirements for having confidence in the accuracy of EC50/IC50 estimates. Two definitions of EC50/IC50s are considered: relative and absolute.

The EC50 defines the half maximal concentration of a drug. In a dose response curve, the EC50 represents the concentration of a drug where 50% of its maximal effect is observed (Figure 1).

EC50 (Effective Concentration 50) indicates the concentration of a drug needed to achieve 50% of its maximum effect. It is a measure of a drug's potency; a lower EC50 value signifies a more …