The fluorenylmethoxycarbonyl protecting group (Fmoc) is a base -labile amine protecting group used in organic synthesis, particularly in peptide synthesis. [1]

Fmoc is a f luorenyl m eth o xy c arbonyl group that forms carbamates with amines. However, as a common theme in protecting groups, alcohols and other nucleophiles can also be protected.

Whilst solid-phase peptide synthesis has undergone significant improvements in the intervening decades, the development of the the fluorenylmethoxycarbonyl protecting group (Fmoc) and …

Fmoc, or 9-fluorenylmethoxycarbonyl, is a commonly used protecting group for amino acids during peptide synthesis. This group allows for the selective protection of the amino group …

The Federal Open Market Committee (FOMC) consists of twelve members--the seven members of the Board of Governors of the Federal Reserve System; the president of the Federal …

New, stable amino-protecting reagents, Boc-DMT and Fmoc-DMT, were prepared, and found to be useful for the introduction of Boc and Fmoc groups into amines. Both the reagents can …

Apr 28, 2025 · The 9-fluorenylmethoxycarbonyl (Fmoc) group serves as a temporary protecting group for the α-amino function during solid-phase peptide synthesis (SPPS). This protecting …

The use of Fmoc chemistry for protection of the alpha amino group has become the preferred method for most contemporary solid and solution phase peptide synthetic processes. Fmoc …

Fmoc is a protecting group commonly used in peptide synthesis that can be removed using piperidine in N,N-dimethylformamide (DMF). It has also been found to have anti-inflammatory …

Jan 5, 2024 · Here, we report a novel Fmoc deprotection method using hydrogenolysis under mildly acidic conditions for the synthesis of Z-Arg-Lys-acyloxymethyl ketone (Z-R-K-AOMK).